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11 jun. 2024

Controlling Electroosmosis in Nanopores Without Altering the Nanopore Sensing Region

Matteo Baldelli, Giovanni Di Muccio, Adina Sauciuc, Blasco Morozzo della Rocca, Francesco Viola, Sébastien Balme, Andrea Bonini, Giovanni Maglia, Mauro Chinappi

Controlling Electroosmosis in Nanopores Without Altering the Nanopore Sensing Region
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Advanced Materials

2 mei 2024

Allostery can convert binding free energies into concerted domain motions in enzymes

Giovanni Maglia, Nicole Galenkamp, Sarah Zernia, Yulan Van Oppen, Andreas Milias-Argeitis

Allostery can convert binding free energies into concerted domain motions in enzymes
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preprint

6 feb. 2024

Visible Light Control over the Cytolytic Activity of a Toxic Pore-Forming Protein

Jana Volarić, Nieck J. van der Heide, Natalie L. Mutter, Douwe F. Samplonius, Wijnand Helfrich, Giovanni Maglia*, Wiktor Szymanski*, and Ben L. Feringa*

Visible Light Control over the Cytolytic Activity of a Toxic Pore-Forming Protein
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ACS Chem. Biol.

23 jan. 2024

Unravelled proteins form blobs during translocation across nanopores

Adina Sauciuc, Jacob Whittaker, Matthijs Tadema, Kasia Tych, Albert Guskov, Giovanni Maglia

Unravelled proteins form blobs during translocation across nanopores
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bioRxiv

31 dec. 2023

Engineered nanopores for exopeptidase protein sequencing

Andrea Bonini, Adina Sauciuc, Giovanni Maglia

Engineered nanopores for exopeptidase protein sequencing
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Nature Methods

17 dec. 2023

Hydrophobically gated memristive nanopores for neuromorphic applications

Gonçalo Paulo, Ke Sun, Giovanni Di Muccio, Alberto Gubbiotti, Blasco Morozzo della Rocca, Jia Geng, Giovanni Maglia, Mauro Chinappi, Alberto Giacomello

Hydrophobically gated memristive nanopores for neuromorphic applications
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Nature Communications

18 okt. 2023

Translocation of linearized full-length proteins through an engineered nanopore under opposing electrophoretic force

Adina Sauciuc, Blasco Morozzo della Rocca, Matthijs Tadema, Mauro Chinappi and Giovanni Maglia

Translocation of linearized full-length proteins through an engineered nanopore under opposing electrophoretic force
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Nature Biotechnology

15 aug. 2023

Seeing the invisibles: detection of peptide enantiomers, diastereomers, and isobaric ring formation in lanthipeptides using nanopores

Roderick Corstiaan Abraham Versloot, Patricia Arias-Orozco, Matthijs Jonathan Tadema, Florian Leonardus Rudolfus Lucas, Xinghong Zhao, Siewert J. Marrink, Oscar Paul Kuipers, Giovanni Maglia

Seeing the invisibles: detection of peptide enantiomers, diastereomers, and isobaric ring formation in lanthipeptides using nanopores
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JACS

17 jul. 2023

Protein sizing with 15-nm conical biological nanopore YaxAB

Sabine Straathof, Giovanni Di Muccio2, Maaruthy Yelleswarapu, Melissa Alzate Banguero2, Carsten Wloka, Nieck Jordy van der Heide, Mauro Chinappi and Giovanni Maglia

Protein sizing with 15-nm conical biological nanopore YaxAB
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ACS Nano

1 mei 2023

Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor

Xialin Zhang, Nicole Stéphanie Galenkamp, Nieck Jordy van der Heide, Julián Moreno, Giovanni Maglia*, and Jørgen Kjems*

Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor
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ACS nano

26 sep. 2022

Nanopore-based technologies beyond DNA sequencing

Yi-Lun Ying, Zheng-Li Hu, Shengli Zhang, Yujia Qing, Alessio Fragasso, Giovanni Maglia, Amit Meller, Hagan Bayley, Cees Dekker and Yi-Tao Long

Nanopore-based technologies beyond DNA sequencing
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Nature Nanotechnology

19 jul. 2022

Unbiased Data Analysis for the Parameterization of Fast Translocation Events through Nanopores.

Lucas FLR , Willems K, Tadema MJ, Tych KM, Maglia G, Wloka C.

Unbiased Data Analysis for the Parameterization of Fast Translocation Events through Nanopores.
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ACS Omega

28 jun. 2022

Quantification of Protein Glycosylation Using Nanopores

Versloot RCA, Lucas FLR, Yakovlieva L, Tadema MJ, Zhang Y, Wood TM, Martin NI, Marrink SJ, Walvoort MTC, Maglia G.

Quantification of Protein Glycosylation Using Nanopores
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ACS Nano

27 jun. 2022

PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood

Dr. Gang Huang, Aderik Voorspoels, Roderick Corstiaan Abraham Versloot, Nieck Jordy van der Heide, Prof. Dr. Enrico Carlon, Dr. Kherim Willems, Prof. Dr. Giovanni Maglia

PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood
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Angewandte Chemie International Edition

17 mrt. 2022

β-Barrel Nanopores with an Acidic-Aromatic Sensing Region Identify Proteinogenic Peptides at Low pH

Versloot RCA, Straathof SAP, Stouwie G, Tadema MJ, Maglia G.

β-Barrel Nanopores with an Acidic-Aromatic Sensing Region Identify Proteinogenic Peptides at Low pH
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ACS Nano

7 mrt. 2022

Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors

Kobauri P, Galenkamp NS, Schulte AM, de Vries J, Simeth NA, Maglia G, Thallmair S, Kolarski D, Szymanski W, Feringa BL.

Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors
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J. Med. Chem.

4 jan. 2022

Single-molecule sampling of dihydrofolate reductase shows kinetic pauses and an endosteric effect linked to catalysis

Galenkamp NS, and Maglia, G.

Single-molecule sampling of dihydrofolate reductase shows kinetic pauses and an endosteric effect linked to catalysis
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ACS Catalysis

17 nov. 2021

Bottom-up fabrication of a proteasome–nanopore that unravels and processes single proteins

Zhang S, Huang G, Versloot RCA, Bruininks BMH, Telles de Souza PC, Marrink SJ and Maglia G.

Bottom-up fabrication of a proteasome–nanopore that unravels and processes single proteins
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Nature Chemistry

21 okt. 2021

In silico assessment of a novel single-molecule protein fingerprinting method employing fragmentation and nanopore detection

de Lannoy C, Lucas FLR, Maglia G, de Ridder D.

In silico assessment of a novel single-molecule protein fingerprinting method employing fragmentation and nanopore detection
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iScience

3 okt. 2021

Protein Identification by Nanopore Peptide Profiling

Lucas FLR, Versloot RCA, Yakovlieva L, Walvoort TCM and Maglia M.

Protein Identification by Nanopore Peptide Profiling
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Nature Commun.

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