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16 aug. 2023

An engineered electroosmotic flow transports linearized native proteins across nanopores under opposing electrophoretic forces

Adina Sauciuc, Blasco Morozzo della Rocca, Matthijs Tadema, Mauro Chinappi and Giovanni Maglia

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Nature Biotechnology (Accepted)

An engineered electroosmotic flow transports linearized native proteins across nanopores under opposing electrophoretic forces

15 aug. 2023

Seeing the invisibles: detection of peptide enantiomers, diastereomers, and isobaric ring formation in lanthipeptides using nanopores

Roderick Corstiaan Abraham Versloot, Patricia Arias-Orozco, Matthijs Jonathan Tadema, Florian Leonardus Rudolfus Lucas, Xinghong Zhao, Siewert J. Marrink, Oscar Paul Kuipers, Giovanni Maglia

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JACS

Seeing the invisibles: detection of peptide enantiomers, diastereomers, and isobaric ring formation in lanthipeptides using nanopores

17 jul. 2023

Protein sizing with 15-nm conical biological nanopore YaxAB

Sabine Straathof, Giovanni Di Muccio2, Maaruthy Yelleswarapu, Melissa Alzate Banguero2, Carsten Wloka, Nieck Jordy van der Heide, Mauro Chinappi and Giovanni Maglia

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ACS Nano

Protein sizing with 15-nm conical biological nanopore YaxAB

1 mei 2023

Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor

Xialin Zhang, Nicole Stéphanie Galenkamp, Nieck Jordy van der Heide, Julián Moreno, Giovanni Maglia*, and Jørgen Kjems*

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ACS nano

Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor

26 sep. 2022

Nanopore-based technologies beyond DNA sequencing

Yi-Lun Ying, Zheng-Li Hu, Shengli Zhang, Yujia Qing, Alessio Fragasso, Giovanni Maglia, Amit Meller, Hagan Bayley, Cees Dekker and Yi-Tao Long

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Nature Nanotechnology

Nanopore-based technologies beyond DNA sequencing

19 jul. 2022

Unbiased Data Analysis for the Parameterization of Fast Translocation Events through Nanopores.

Lucas FLR , Willems K, Tadema MJ, Tych KM, Maglia G, Wloka C.

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ACS Omega

Unbiased Data Analysis for the Parameterization of Fast Translocation Events through Nanopores.

28 jun. 2022

Quantification of Protein Glycosylation Using Nanopores

Versloot RCA, Lucas FLR, Yakovlieva L, Tadema MJ, Zhang Y, Wood TM, Martin NI, Marrink SJ, Walvoort MTC, Maglia G.

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ACS Nano

Quantification of Protein Glycosylation Using Nanopores

27 jun. 2022

PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood

Dr. Gang Huang, Aderik Voorspoels, Roderick Corstiaan Abraham Versloot, Nieck Jordy van der Heide, Prof. Dr. Enrico Carlon, Dr. Kherim Willems, Prof. Dr. Giovanni Maglia

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Angewandte Chemie International Edition

PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood

17 mrt. 2022

β-Barrel Nanopores with an Acidic-Aromatic Sensing Region Identify Proteinogenic Peptides at Low pH

Versloot RCA, Straathof SAP, Stouwie G, Tadema MJ, Maglia G.

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ACS Nano

β-Barrel Nanopores with an Acidic-Aromatic Sensing Region Identify Proteinogenic Peptides at Low pH

7 mrt. 2022

Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors

Kobauri P, Galenkamp NS, Schulte AM, de Vries J, Simeth NA, Maglia G, Thallmair S, Kolarski D, Szymanski W, Feringa BL.

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J. Med. Chem.

Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors

4 jan. 2022

Single-molecule sampling of dihydrofolate reductase shows kinetic pauses and an endosteric effect linked to catalysis

Galenkamp NS, and Maglia, G.

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ACS Catalysis

Single-molecule sampling of dihydrofolate reductase shows kinetic pauses and an endosteric effect linked to catalysis

17 nov. 2021

Bottom-up fabrication of a proteasome–nanopore that unravels and processes single proteins

Zhang S, Huang G, Versloot RCA, Bruininks BMH, Telles de Souza PC, Marrink SJ and Maglia G.

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Nature Chemistry

Bottom-up fabrication of a proteasome–nanopore that unravels and processes single proteins

21 okt. 2021

In silico assessment of a novel single-molecule protein fingerprinting method employing fragmentation and nanopore detection

de Lannoy C, Lucas FLR, Maglia G, de Ridder D.

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iScience

In silico assessment of a novel single-molecule protein fingerprinting method employing fragmentation and nanopore detection

3 okt. 2021

Protein Identification by Nanopore Peptide Profiling

Lucas FLR, Versloot RCA, Yakovlieva L, Walvoort TCM and Maglia M.

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Nature Commun.

Protein Identification by Nanopore Peptide Profiling

13 aug. 2021

Automated Electrical Quantification of Vitamin B1 in a Bodily Fluid using an Engineered Nanopore-Sensor

Lucas FLR, Piso TRC, van der Heide NJ, Hermans J, Galenkamp NS, Wloka C and Maglia G.

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Angewandte Chemie International Edition

Automated Electrical Quantification of Vitamin B1 in a Bodily Fluid using an Engineered Nanopore-Sensor

6 jun. 2021

The emerging landscape of single-molecule protein sequencing technologies

Alfaro JA, et al.

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Nature Methods

The emerging landscape of single-molecule protein sequencing technologies

31 mei 2021

The Manipulation of the Internal Hydrophobicity of FraC Nanopores Augments Peptide Capture and Recognition

Lucas FLR, Sarthak K, Lenting EM, Coltan D, van der Heide NJ, Versloot RCA, Aksimentiev A, Maglia G.

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ACS Nano

The Manipulation of the Internal Hydrophobicity of FraC Nanopores Augments Peptide Capture and Recognition

20 apr. 2021

Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic

Lauxen AI, Kobauri P, Wegener M, Hansen MJ, Galenkamp NS, Maglia G, Szymanski W, Feringa BL, Kuipers OP.

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Pharmaceuticals

Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic

18 dec. 2020

Autonomous and Active transport operated by an entropic DNA piston

Bayoumi M, Nomidis KS, Maglia G, Willems K, Carlon E and Maglia G.

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Nano Letters

Autonomous and Active transport operated by an entropic DNA piston

12 sep. 2020

Preparation of Fragaceatoxin C (FraC) Nanopores

Mutter NL, Huang G, van der Heide NJ, Lucas FLR, Galenkamp NS, Maglia G, Wloka C.

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Methods Mol Biol.

Preparation of Fragaceatoxin C (FraC) Nanopores
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